First factor the numerator and denominator.

52 = 2 · 2 · 13

100 = 2 · 2 · 5 · 5

The GCF is the product of the common prime factors in each term.

GCF = 2 · 2 = 4 \ \

Divide the numerator and the denominator by GCF.

       (Divide)

Simpliest form of the fraction is .